What is Dupuytren's disease?

Dupuytren's disease is an abnormal thickening of the fascia (the tissue between the skin and the tendons in the palm) that may limit movement of one or more fingers.  In some patients, a cord forms beneath the skin that stretches from the palm into the fingers.  The cord can cause the fingers to bend into the palm so they cannot be fully straightened.  Sometimes, the disease will cause thickening over the knuckles of the finger.  It can also occur in the soles of the feet.

What Causes it?
The exact cause of this disease is unknown. While the development of Dupuytren's cords or nodules may occur following trauma or surgery, the exact relationship is uncertain. The disease is usually painless, and at this time there is no permanent cure.